Organizing notes and/or…
What I learn (try to figure out and detail) along the way in my study about obesity and the microbiome/gut bacteria …
Newborns, breast milk and HMO’s…
Oligosaccharide from the Greek, oligos, a few, and sácchar, sugar.
Human milk oligosaccharide (HMO) are sugar molecules found only in human breast milk. HMO’s, while indigestible in a newborn, encourage the growth of health promoting bifidobacteria. Think: fertilizer designed for fitness enhancing microbes.
Stuff I find particularly interesting…
Breast feeding promotes a diversity in the microbiome that may set up an individual for protection against future obesity (amongst other things).
Breast milk varies over the period of lactation and the growth of bacteria varies in different populations.
And then there are the short-chain fatty acids (SCFA) …
SCFA are another product of microbial (friendly gut bacteria) fermentation (of indigestible dietary fibers). This source energy for the cells lining the colon kill pathogens and protects against dysbiosis.
Included in my drawing are the 3 most common examples of SCFA’s which are butyrate↑, propionate↓ and acetate↓↓.
(Yes…fun to draw out and paint all the ball and stick models.)
The right food early in life trains the immune system via the microbiome.
Changes in diet (those SCFA) drive changes in gut microbes. Fiber rich foods (plant based) allow host and microbes to have mutualistic relationship (cooperation).
Microbes harm and/or help us (the host).
Junk food allows for conflict (harm).
…and then there’s hormones…
Does some food fuel pathogens and promote their growth?
Does some food inhibit or kill pathogens?
Do pathogens play a role in obesity?
#PortraitOfVeronica #GottaHaveArt #ThisStuffIsFrickinComplicated
ps. The title of the post came after a Yoga class the day after the holiday.
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You might especially enjoy this attempt to catalog some ‘best practices’ in collaboration and teamwork into the form of a Pattern Language (free, no ads). Here’s an index — https://petersironwood.com/2018/06/29/pattern-language-summary