microscopic organisms in my studio (here, there and everywhere)

In a recent interview Nicole begins by asking, “Who are you and what do you do?” I wonder if she knows I consider these questions all the time.

Who am I? What am I? What is this world? What is my relationship to it?

This summer, as artist-in-residence at the Tempe Center for the Arts, I study and draw out  the incredible human brain. My answer (to the set up of questions) then, could go something like – I am a nervous system. I am neurons and glia firing up a brain. 

As of recent I study microorganisms: bacteria, viruses, fungi, archaea and protists. Today – I am an (human) organism made up of (hosting) micro (too small to see without magnification) organisms.

Note: My series of compositions include external and internal views and are ginormous considering…

In the course of this current interest (more like revelation) in microorganisms, I come across a virus that takes me back to the residency research where I look at the healthy brain and the diseased brain (In general I looked at Dementia, in particular I tried to understand Alzheimer’s Disease).

Meet M13 (Munich13), a bacteriophage (or simply a phage).

External (proteins)

A phage is a virus that infects and replicates within bacteria. M13 invades E Coli.

M13 catches my attention when I come across an article explaining how the virus dissolves (in laboratory studies) amyloid-beta plaques and tao tangles.  #combatneurodegenerativedisease  #Alzheimer’s  #Parkinson’s. #Huntington’s
#Creutzfeldt-Jakob

Here (↑ ↓) you have my best interpretation of the M13 filamentous bacteriophage.

Internal structure (composed of a single stranded DNA molecule encased in a thin flexible tube (protein coat)

…Life (microscopic organisms) in the studio (here, there and everywhere).

#microorganisms #microbiota #humanmicrobiome #weareone

a bacterium – the coiled gatekeeper

Meet Helicobacter pylori, AKA H. pylori – a bacterium found in the mucous lining of the stomach (in at least 50% -60% of the world’s population).

External (top image) and internal (bottom image) study of H. pylori bacteria.

Helicobacter from the Greek, means spiral or coil. Pylori related to pylouros, the opening or junction leading from the stomach into the duodenum, also from the Greek, translates to gatekeeper.

My studies include bacterial cell basics: plasma membrane, cell wall, ribosomes, cytoplasm and nucleoid (no enclosed nucleus).

H.Pylori: external (top), internal structures (bottom)

I remember once-upon-a-time studying single-celled organisms. I always liked the word flagella and still it manages to get my attention (determines compositional layout). The whip-like appendages support locomotion (moving, pushing, swimming) and are also sensitive to temperature and chemistry.

I wonder – in the case of  H. pylori – should this particular microorganism really be on the move? 

Flagella – a whip-like appendage.

I work from images that include the pili (another cool word…related to pilus and Latin for hair) while other photos suggest the bacteria to be a smooth coil. In each study I take liberty with color and I include the hair-like pili in one drawing, for the added rhythmic line and texture.

Some of my favorite bacteria (in name only) have a lot in common (of course they do, they’re bacteria). To my untrained (in bacteria) eyes (perhaps even to the trained eye) my study of H. pylori could resemble E-Coli. Perhaps one might even pass for Lactobacillus and another for Salmonella.

As my study evolves – Surface of bacteria

The human body (yours and mine) is home to loads of (100 trillion) bacteria.  We host colonies of microorganisms! They live in us and on us.

Are they harmful? They can be. Are they beneficial? They might be. For example, H. pylori in the stomach can lead to duodenal ulcers and stomach cancer. Did I mention this particular bacteria adapts to an acidic environment? Note – it does not always produce disease.

Process photos… study continues to evolve…internal structure of bacteria

I think about the creative process a lot, laying out careful design only to sometimes rub it out quickly. It is, for me, a continuous mix of control and freedom.

Helicobacter pylori, Coiled Gatekeeper, are you a natural expression of the creative process?


Back in the studio…
I am in the stomach with this bacteria. I plan to look at viruses, fungi and archaea too. Let’s see where they take me. At some point I will be returning to the brain – with a new perspective.
#GutBrainAxis #Microbiome